RESUMEN
Even though organizations encourage the dissemination of knowledge and information among organizational members, the phenomenon of knowledge hiding still exists widely in organizations. The consequences of leader-signaled knowledge hiding are more destructive to the workplace than the consequences of employees' knowledge hiding. It is particularly necessary to explore the influence mechanism of leader-signaled knowledge hiding on employees' work behavior. Drawing on Conservation of Resources theory, this study establishes a moderated mediation model with emotional exhaustion as a mediating variable and supervisor-subordinate guanxi as a moderating variable. This study focuses on the consequences of leader-signaled knowledge hiding and divides leader-signaled knowledge hiding into self-practiced knowledge hiding and explicit knowledge hiding. Based on the results of 440 questionnaires from tourism employees, it is shown that leader-signaled knowledge hiding has a positive impact on employees' work withdrawal behavior. Specifically, leader's self-practiced knowledge hiding has a greater direct impact on employees' work withdrawal behavior, while leader's explicit knowledge hiding has a greater direct impact on employees' emotional exhaustion. Emotional exhaustion plays a key mediating role in the relationship between leader-signaled knowledge hiding (i.e., self-practiced knowledge hiding and explicit knowledge hiding) and employees' work withdrawal behavior. Supervisor-subordinate guanxi significantly moderates the positive relationship between leader-signaled knowledge hiding (i.e., self-practiced hiding and explicit knowledge hiding) and employees' emotional exhaustion. This study is an extension of previous research on knowledge hiding. The results provide a reference for leaders to deal with knowledge hiding and improve organizational knowledge management ability.
RESUMEN
As a result of social change, the issues, such as the complexity of family structure and increasing student problems, are becoming more complicated. Both schools and parents have high expectations of teachers and expect them to solve the problems. Considering the many different factors involved in this issue, this could lead to a psychological and physiological imbalance in teachers, especially in relation to their emotions which results in role ambiguity. The participants of this study consisted of teachers in business administration departments of universities in China. During the data collection, 450 copies of the questionnaire were distributed. A total of 363 valid copies were retrieved, with a retrieval rate of 81%. It can be concluded that the results of this study can help national university faculty present professional spirit and attitude toward the professional service, which in turn promotes the standard of national education in universities.
RESUMEN
Renal fibrosis is an important pathological biomarker of chronic kidney disease (CKD). Stimulator of interferon genes/TANK binding kinase 1 (STING/TBK1) axis has been identified as the main regulator of innate immune response and closely related to fibrotic disorder. However, the role of STING/TBK1 signaling pathway in kidney fibrosis is still unknown. In this study, we investigated the effect of pharmacological inhibition of STING/TBK1 signaling on renal fibrosis induced by folic acid (FA). In mice, TBK1 was significantly activated in interstitial cells of FA-injured kidneys, which was markedly inhibited by H-151 (a STING inhibitor) treatment. Specifically, pharmacological inhibition of STING impaired bone marrow-derived fibroblasts activation and macrophage to myofibroblast transition in folic acid nephropathy, leading to reduction of extracellular matrix proteins expression, myofibroblasts formation and development of renal fibrosis. Furthermore, pharmacological inhibition of TBK1 by GSK8612 reduced myeloid myofibroblasts accumulation and impeded macrophage to myofibroblast differentiation, resulting in less deposition of extracellular matrix protein and less severe fibrotic lesion in FA-injured kidneys. In cultured mouse bone marrow-derived monocytes, TGF-ß1 activated STING/TBK1 signaling. This was abolished by STING or TBK1 inhibitor administration. In addition, GSK8612 treatment decreased levels of α-smooth muscle actin and extracellular matrix proteins and prevents bone marrow-derived macrophages to myofibroblasts transition in vitro. Collectively, our results revealed that STING/TBK1 signaling has a critical role in bone marrow-derived fibroblast activation, macrophages to myofibroblasts transition, and kidney fibrosis progression.
RESUMEN
The organic food industry in China has been developing fast with the increasing consumer demand for healthier, safer, and more nutritious foods since the epidemic outbreak. It is of great significance to understand the psychological preference of consumers for organic food and adjust the marketing strategy accordingly. In this study, we adopted the multi-group structural equation model (SEM) to analyze 571 questionnaire data and explored the effects of consumers' perception on the sensory appeal of organic food, perception on promotional stimulation, positive emotion, and perceived social value on the purchase intention of organic food. Based on the Stimulus-Organism-Response (S-O-R) model, this study divides the route affecting organic consumption behavior into the rational route and emotional route. It was proved that the emotional route (positive emotion) has a greater impact on the purchase intention of organic food than the rational route (perceived social value). In addition, there are different purchase intentions among different product types. Specifically, compared with organic tea, positive emotion has a greater effect on the purchase intention for organic rice. This study provides an important reference for the organic food-marketing strategy of enterprises.
